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Cholic acid resistance and the adherence ability of Bifidobacterium pseudocaenulatum G4


Sulaiman, Ali Qahtan and Jalilian, Farid Azizi and Mustafa, Shuhaimi and Sekawi, Zamberi and Mohd Ghazali, Hasanah and Meor Hussin, Anis Shobirin and Abd Manap, Mohd Yazid (2009) Cholic acid resistance and the adherence ability of Bifidobacterium pseudocaenulatum G4. African Journal of Biotechnology, 8 (19). art. no. F6694EB8582. pp. 5066-5070. ISSN 1684–5315


The adherence capacity of Bifidobacterium longum BB536 and Bifidobacterium pseudocatenulatum G4 on HT-29 human epithelium cell line with the presence of cholic acid were assessed. B. longum BB536 showed a higher adhesion level on HT-29 human epithelium cell line compared to B. psudocatenulatum G4. However, in the presence of physiological concentration (0.094 and 0.94 μM) of cholic acid, the adhesion level of Bifidobacterium strains dropped between 5 and 55% respectively, depending on pH, time and strain. The adaptation of Bifidobacterium strains to cholic acid was shown to be increased with time. It was concluded that the acquisition of cholic acid resistance by those Bifidobacterium strains promoted changes in the adhesion ability on HT-29 human epithelium cell line.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
Faculty of Medicine and Health Science
Halal Products Research Institute
DOI Number: https://doi.org/10.5897/AJB09.308
Publisher: Academic Journals
Keywords: Adhesion; Bifidobacterium; Cholic acid
Depositing User: Khairil Ridzuan Khahirullah
Date Deposited: 06 Nov 2013 04:54
Last Modified: 31 May 2016 06:01
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.5897/AJB09.308
URI: http://psasir.upm.edu.my/id/eprint/13591
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