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Chemical constituents and bioactivities of Kaempferia rotunda L.


Md. Sukari, Mohd. Aspollah and Neoh, Bee Keat and Tang, Sook Wah and Riyanto, Sugeng and Lajis, Md. Nordin and Cheng, Gwendoline Lian Ee (2009) Chemical constituents and bioactivities of Kaempferia rotunda L. Ultra Scientist of Physical Sciences, 21 (3). pp. 699-706. ISSN 0970-9150


Phytochemical study on the rhizomes of Kaempferia rotunda originated from Yogyakarta, Indonesia has led to the isolation of crotepoxide, benzoic acid, tetracosanoic acid, b-sitosterol and stigmasterol. Tetracosanoic acid and benzoic acid have never been reported for this species previously. Bioactivity studies on the extracts and isolated compound (crotepoxide) were carried out. Extracts and crotepoxide from K. rotunda were not active against HL-60 (human promyelocytic leukemic) cell line in cytotoxic testing. However, the non-polar extract demonstrated moderate inhibition in antimicrobial assay whereas in FTC antioxidant testing, all extracts exhibited strong activity as compared to vitamin E.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
Publisher: Ultra Scientist of Physical Sciences
Keywords: Kaempferioa rotunda; Zingiberaceae; Antioxidant; Antimicrobial.
Depositing User: Nida Hidayati Ghazali
Date Deposited: 02 Apr 2014 09:09
Last Modified: 22 Oct 2015 06:04
URI: http://psasir.upm.edu.my/id/eprint/13570
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