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Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.


Abdul Razak , Hairil Rashmizal and Abdul Rahim, Noraini and Rossetti, Claudio and Nordin, Abdul Jalil (2010) Brown fat uptake of 18F-FDG on dual time point PET/CT imaging. Singapore Medical Journal, 51 (2). e37-e39. ISSN 0037-5675


The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/ CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax) with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two scans ranged from -20 percent to +20 percent. Based on our observation, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Singapore Medical Association
Keywords: 18F-FDG; Brown fat; Dual time point imaging; PET/CT
Depositing User: Raja Norazlinda Raja Azenam
Date Deposited: 13 Nov 2014 07:25
Last Modified: 26 Oct 2015 06:28
URI: http://psasir.upm.edu.my/id/eprint/13459
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