UPM Institutional Repository

Antifungal properties of Allium sativum extracts on Candida species


Low, Chen Fei and Yong, Phelim Voon Chen and Ahmad, Zuraini and Othman, Fauziah and Chong, Pei Pei (2008) Antifungal properties of Allium sativum extracts on Candida species. Journal of Tropical Medicinal Plants, 9 (1). pp. 43-48. ISSN 1511-8525


Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium sativum (Garlic) extracts on the three Candida species through paper disc diffusion method showed that all the three Candida species were resistant to A. indica and P. pellucida, but susceptible to A. sativum extract. Subsequently, the effect of different concentrations of garlic extract on the growth of C. albicans was evaluated to determine the IC50 and LD50. The effect of garlic extract suggests that sublethal doses can reduce the colonization of Candida species in the oral cavity of humans by suppressing the virulent hyphal growth form.

Download File

PDF (Abstract)
Antifungal properties of Allium sativum extracts on Candida species.pdf

Download (179kB) | Preview

Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Total Health Concept Sdn.bhd
Keywords: Azadirachta indica; Peperomia pellucida; Allium sativum; Candida species
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 07 Jun 2015 03:28
Last Modified: 05 Oct 2015 07:52
URI: http://psasir.upm.edu.my/id/eprint/13143
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item