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Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl


Citation

Al-Haj, Nagi Ahmed and Mashan, Nurmas Izaty and Shamsudin , Mariana Nor and Mohamad, Habsah and Vairappan, Charles S. and Sekawi, Zamberi (2009) Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl. Research Journal of Biological Sciences, 4 (5). pp. 580-584. ISSN 1815-8846; ESSN: 1993-6087

Abstract / Synopsis

Gram-positive bacteria are more sensitive to antibiotics than gram-negative bacilli because of the lack of outer membrane which prevent easy access of the drug into the bacterial cells. However, there are many gram-positive organisms with natural, intrinsic resistance to antimicrobials. In addition, these bacteria are able to acquire resistance to frequently used drugs rapidly through selective pressure of the environment and also via the genetic evolution of bacteria. The resistance of those bacteria to antibacterial agents is mediated by antibiotic resistant genes. Therefore, the current study was designed to explore the effect of seaweed extracts on several antibiotic resistant genes in Staphylococcus aureus mec genes mecA, mecR1 and mecI that regulate the expression of methicillin resistance was investigated by PCR.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Institute of Bioscience
Publisher: Medwell Journals
Keywords: Methicillin resistanc staphylococcus aureus seaweed; Polymerase chain reaction; Gene; Malaysia
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 07 Jun 2015 10:43
Last Modified: 19 Nov 2015 15:33
URI: http://psasir.upm.edu.my/id/eprint/13134
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