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Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum


Ismail, Intan Safinar and Nagakura, Yuta and Hirasawa, Yusuke and Hosoya, Takahiro and Mohd Lazim, Mohd Izwan and Lajis, Md. Nordin and Morita, Hiroshi (2009) Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum. Tetrahedron Letters, 50 (34). pp. 4830-4832. ISSN 0040-4039; ESSN: 1873-3581


Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity against human blood premyelocytic leukemia cells.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
Institute of Bioscience
DOI Number: https://doi.org/10.1016/j.tetlet.2009.05.110
Publisher: Pergamon Press
Keywords: Acutaxylines A; Acutaxylines B; Triterpenes; Dysoxylum acutangulum
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 06 Jun 2015 06:34
Last Modified: 29 Sep 2015 02:57
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.tetlet.2009.05.110
URI: http://psasir.upm.edu.my/id/eprint/12927
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