Successful treatment of fetal circular shunt using indomethacin in Ebstein anomaly with early hydrops

Citation

Yubbu, Putri and Pang, K. Y. and Koh, G. T. and Valayudham, Vairavan Ramesh (2026) Successful treatment of fetal circular shunt using indomethacin in Ebstein anomaly with early hydrops. Progress in Pediatric Cardiology, 84. art. no. 101963. pp. 1-4. ISSN 1058-9813; eISSN: 1558-1519

Abstract

Circular shunt in Ebstein anomaly is associated with high in-utero mortality. Transplacental indomethacin has been reported to improve perinatal outcomes by inducing ductus arteriosus constriction. We report two fetuses with Ebstein anomaly and circular shunt treated with antenatal oral indomethacin: one diagnosed at 33 weeks' gestation with early hydrops and another at 29 weeks' gestation with advanced hydrops. The markedly different outcomes illustrate the potential benefit of prenatal indomethacin when initiated early in the disease course and emphasize the importance of early fetal cardiology referral and proactive management in this high-risk population.

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Additional Metadata

Item Type:	Article
Subject:	Pediatrics, Perinatology and Child Health
Subject:	Cardiology and Cardiovascular Medicine
Divisions:	Faculty of Medicine and Health Science Hospital Sultan Abdul Aziz Shah (UPM)
DOI Number:	https://doi.org/10.1016/j.ppedcard.2026.101963
Publisher:	Elsevier Ireland
Keywords:	Circular shunt; Congenital heart disease; Ebstein anomaly; Fetal; Indomethacin
Sustainable Development Goals (SDGs):	SDG 3: Good Health and Well-being, SDG 5: Gender Equality, SDG 10: Reduced Inequalities
Depositing User:	Ms. Siti Radziah Mohamed@mahmod
Date Deposited:	26 Aug 2026 05:34
Last Modified:	26 Aug 2026 05:34
Altmetrics:	https://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.ppedcard.2026.101963
URI:	http://psasir.upm.edu.my/id/eprint/127920
Statistic Details:	View Download Statistic

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