Tea polyphenols and iron oxide nanoparticles: therapeutic benefits, microbiota interactions, and proteomic perspectives

Combining green tea polyphenols (GTPs) in iron oxide nanoparticles (IONPs) has attracted significant interest due to its potential therapeutic implications. This review investigates the beneficial effects of conjugating IONPs with polyphenols, highlighting their enhanced bioavailability and efficacy. The relationship between tea polyphenols and intestinal microbiota has been clarified by metagenomics research, highlighting how these relationships improve bioavailability. Moreover, studies elucidating the impact of metallic and magnetic nanoparticles on the composition of the gut microbiota provide insight into their function in regulating microbial diversity. Proteomic analyses have provided valuable insights into the molecular mechanisms underlying polyphenol-metallic nanoparticle interactions, offering a comprehensive understanding of their biological processes at the protein level. The study of polyphenol-nanoparticle interactions using metagenomics and proteomic approaches provides a promising direction for further research into possible medicinal uses and therapeutic applications.

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