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Evaluating the association between maternal paracetamol intake and childhood asthma: a review for prenatal nursing management


Citation

Ramli, Rosmaliza and Mohamad Zainal, Nurul Hayati and Noel, Jovita Ann and Shahidan, Wan Nazatul Shima and T Ismail @ T Manah, Tuan Nadrah Naim and Hasbullah, Nurulezah (2025) Evaluating the association between maternal paracetamol intake and childhood asthma: a review for prenatal nursing management. Malaysian Journal of Medicine and Health Sciences, 21 (3). pp. 497-511. ISSN 1675-8544; eISSN: 2636-9346

Abstract

Nurses are integral members of the healthcare team and play an important role in providing healthcare information to pregnant women. Recent evidence suggests that the use of paracetamol in pregnant women increases the risk for childhood asthma in offspring. This review aimed to provide an updated evaluation of maternal paracetamol intake and its association with childhood asthma in offspring. Using PubMed, Scopus, and Web of Science scientific databases, we screened relevant articles on maternal paracetamol use and childhood asthma. After applying inclusion and exclusion criteria, 19 articles were selected for review. Most studies support the association between maternal paracetamol use and childhood asthma in offspring. However, interpreting these findings requires caution, as factors such as maternal asthma history, emotional state, and pain levels may influence the observed associations. Therefore, the use of paracetamol for fever and pain management in pregnant women should be approached judiciously.


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Additional Metadata

Item Type: Article
Subject: Medicine (all)
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.47836/mjmhs.21.3.58
Publisher: Universiti Putra Malaysia Press
Keywords: Acetaminophen; Childhood asthma; Maternal; Paracetamol; Prenatal exposure
Sustainable Development Goals (SDGs): SDG 3: Good Health and Well-being, SDG 5: Gender Equality, SDG 4: Quality Education
Depositing User: Ms. Nur Faseha Mohd Kadim
Date Deposited: 08 Jul 2026 07:15
Last Modified: 08 Jul 2026 07:15
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.47836/mjmhs.21.3.58
URI: http://psasir.upm.edu.my/id/eprint/126913
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