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Antibacterial and anticancer activity of magnesium oxide and silver nanoparticles prepared by eco-friendly methods


Citation

Almohana, Abothur and A. Al-Kelaby, Khalida Kadhim and Che Abdullah, Che Azurahanim and Almohana, Ali and Khamees, Entidhar Jasim (2026) Antibacterial and anticancer activity of magnesium oxide and silver nanoparticles prepared by eco-friendly methods. BioNanoScience, 16. art. no. 411. ISSN 2191-1630; eISSN: 2191-1649

Abstract

In this work, magnesium oxide (MgO)- and silver (Ag)-nanoparticles (NPs) are synthesized from plant extracts by means of green synthesis methods to investigate their optical and antibacterial activities. In accordance with X-ray diffraction spectroscopy (XRD) analysis, both of the samples have face-centered cubic (fcc) structure. The presence of absorption bands of Ag and MgO, respectively in the Fourier transform infrared spectroscopy (FTIR) spectra of Ag and MgO-NPs confirm more the successful formation of those materials. Both the samples reveal different morphologies where an interwoven network on which the NPs of Ag are located is observed for Ag nanostructures and a flower-like morphology is seen for MgO-NPs. Our prepared Ag and MgO-NPs exhibit excellent optical properties, which make them suitable for photocatalytic activities. Both of the samples show intense peaks in ultraviolet (UV) and visible regions, as respectively shown by UV-visible and photoluminescence (PL) spectroscopy. Ag and MgO-NPs also demonstrate extraordinary antibacterial activities against Escherichia coli as well as Staphylococcus aureus strains. Moreover, they possess considerable cytotoxicity and low cell viability, which make them suited as anticancer agents.


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Additional Metadata

Item Type: Article
Subject: Bioengineering
Subject: Biomedical Engineering
Divisions: Faculty of Science
DOI Number: https://doi.org/10.1007/s12668-026-02660-z
Publisher: Springer
Keywords: Antibacterial; Anticancer; Magnesium oxide; Nanotechnology; Silver
Sustainable Development Goals (SDGs): SDG 3: Good Health and Well-being
Depositing User: Ms. Siti Radziah Mohamed@mahmod
Date Deposited: 15 Jul 2026 07:12
Last Modified: 15 Jul 2026 07:12
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1007/s12668-026-02660-z
URI: http://psasir.upm.edu.my/id/eprint/126750
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