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Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma


Citation

Ban, Kechen (2002) Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma. PhD thesis, Universiti Putra Malaysia.

Abstract / Synopsis

Hepatocellular carcinoma (HCC) is an extremely difficult disease to manage and one of the ten most common cancers in Malaysia. However, the molecular mechanisms that contribute to tumour progression in hepatocarcinogenesis remain unknown. In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. Despite efforts made in this area of research, the relationship between the related genes of Wnt signaling pathway is still far from comprehensive. By employing immunohistochemistry and DNA sequencing, some related proteins and genes of the Wnt signaling pathway were investigated in 23 paired HCC and adjacent liver specimens from a tertiary referral centre in Malaysia.


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Additional Metadata

Item Type: Thesis (PhD)
Call Number: FPSK(P) 2002 1
Chairman Supervisor: Associate Professor Dr. Seow Heng Fong
Divisions: Faculty of Medicine and Health Science
Depositing User: Mohd Nezeri Mohamad
Date Deposited: 18 Jul 2011 02:07
Last Modified: 08 Aug 2011 04:43
URI: http://psasir.upm.edu.my/id/eprint/11271
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