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Systematic review on e-cigarette and its effects on weight gain and adipocytes


Citation

Hod, Rafidah and Mohd Nor, Nurul Huda and Maniam, Sandra (2022) Systematic review on e-cigarette and its effects on weight gain and adipocytes. PLoS ONE, 17 (7). art. no. 270818. pp. 1-17. ISSN 1932-6203

Abstract

Smoking and obesity are leading causes of morbidity and mortality worldwide. E-cigarette which was first introduced in 2000s is perceived as an effective alternative to conventional tobacco smoking. Limited knowledge is available regarding the risks and benefits of e-cigarettes. This study systematically reviews the current literature on the effects of e-cigarettes on body weight changes and adipocytes. The search was performed using OVID Medline and Scopus databases and studies meeting the inclusion criteria were independently assessed. This review included all English language, empirical quantitative and qualitative papers that investigated the effects of e-cigarettes on bodyweight or lipid accumulation or adipocytes. Literature searches identified 4965 references. After removing duplicates and screening for eligibility, thirteen references which involve human, in vivo and in vitro studies were reviewed and appraised. High prevalence of e-cigarette was reported in majority of the cross sectional studies conducted among respondent who are obese or overweight. More conclusive findings were identified in in vivo studies with e-cigarette causing weight decrease. However, these observations were not supported by in vitro data. Hence, the effect of e-cigarette on body weight changes warrants further investigations. Well-designed population and molecular studies are needed to further elucidate the role of e-cigarettes in obesity.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1371/journal.pone.0270818
Publisher: Public Library of Science
Keywords: E-cigarette; Smoking; Obesity; Tobacco
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 13 Jun 2023 03:12
Last Modified: 13 Jun 2023 03:12
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1371/journal.pone.0270818
URI: http://psasir.upm.edu.my/id/eprint/103423
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