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Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies


Citation

Molujin, Arnold Marshall and Abbasiliasi, Sahar and Nurdin, Armania and Lee, Ping-Chin and Gansau, Jualang Azlan and Jawan, Roslina (2022) Bacteriocins as potential therapeutic approaches in the treatment of various cancers: a review of in vitro studies. Cancers, 14 (19). art. no. 4758. pp. 1-14. ISSN 2072-6694

Abstract

Cancer is regarded as one of the most common and leading causes of death. Despite the availability of conventional treatments against cancer cells, current treatments are not the optimal treatment for cancer as they possess the possibility of causing various unwanted side effects to the body. As a result, this prompts a search for an alternative treatment without exhibiting any additional side effects. One of the promising novel therapeutic candidates against cancer is an antimicrobial peptide produced by bacteria called bacteriocin. It is a non-toxic peptide that is reported to exhibit potency against cancer cell lines. Experimental studies have outlined the therapeutic potential of bacteriocin against various cancer cell lines. In this review article, the paper focuses on the various bacteriocins and their cytotoxic effects, mode of action and efficacies as therapeutic agents against various cancer cell lines.


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Official URL or Download Paper: https://www.mdpi.com/2072-6694/14/19/4758

Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Halal Products Research Institute
DOI Number: https://doi.org/10.3390/cancers14194758
Publisher: MDPI
Keywords: Lactic acid bacteria; Bacteriocin; Cancer; Anticancer; New treatment
Depositing User: Ms. Nur Faseha Mohd Kadim
Date Deposited: 29 Nov 2023 06:41
Last Modified: 29 Nov 2023 06:41
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/cancers14194758
URI: http://psasir.upm.edu.my/id/eprint/100506
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