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Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae)


Citation

Susidarti, Ratna Asmah (2003) Chemical Constituents and Biological Activities of Micromelum Minutum (Rutaceae) and Two Eugenia Species (Myrtaceae). PhD thesis, Universiti Putra Malaysia.

Abstract / Synopsis

Drug discovery has been a goal of mankind since prehistoric times. Plants continue to be an exceptionally viable source of biologically active natural products. However, only small portion of the higher plants has been phytochemically and pharmacologically investigated. Two separate collections of Micromelum minutum from Sabah and two Eugenia species, E. chlorantha and E. cumingiana collected from the northern forest of Perak were subjected to phytochemical investigation with the isolation of a number of compounds. The structures of these compounds were elucidated by using spectroscopic methods such as IR, UV, NMR, MS and also by comparison with previous reports. The crude extracts, essential oil and isolated compounds from these plant materials were evaluated for their antiinflammatory, cytotoxic and antimicrobial activities using carrageenan-induced rat paw oedema, MTT and disc diffusion methods, respectively. Some isolated compounds showed interesting biological activities.


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Additional Metadata

Item Type: Thesis (PhD)
Subject: Rutaceae.
Subject: Myrtaceae.
Call Number: FSAS 2003 20
Chairman Supervisor: Professor Dr. Mawardi Rahmani
Divisions: Faculty of Environmental Studies
Depositing User: Muizzudin Kaspol
Date Deposited: 16 Feb 2011 16:25
Last Modified: 27 Aug 2012 15:53
URI: http://psasir.upm.edu.my/id/eprint/9560
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