Nagalingam, Saravanan (2001) Studies on coordination chemistry and bioactivity of complexes of Ni(II) and Cu(II) containing some nitrogen-sulphur donor ligands. Masters thesis, Universiti Putra Malaysia.
Several Schiff bases of S-benzyldithiocarbazate (SBDTC) and Smethyldithiocarbazate (SMDTC) have been synthesised. Complexes of NiCll) and Cu(IT) were prepared. These compounds were characterised by elemental analyses and various physico-chemical techniques. The Schiff bases and their metal complexes were tested to evaluate their cytotoxic, antimicrobial and antioxidant activities. Cytotoxic screening was carried out against the T-Iymphoblastic leukemic cells (CEM-SS) and colon cancer cells (HT-29). Antimicrobial screening was carried out against four bacteria and four fungi. The nickelCTI) complexes are four- and five- coordinated while the copper(TI) complex is five-coordinated.
|Item Type:||Thesis (Masters)|
|Subject:||Schiff bases - Synthesis|
|Chairman Supervisor:||Associate Professor Dr. Md. Tofazzal Hossain Tarafder|
|Call Number:||FSAS 2001 37|
|Faculty or Institute:||Faculty of Environmental Studies|
|Deposited By:||Tuan Norasiah Tuan Yaacob|
|Deposited On:||19 Jan 2011 12:51|
|Last Modified:||15 May 2012 12:20|
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