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The effect of topical application of Malaysian honey on burn wound healing


Citation

Mohd Zohdi, Rozaini and Abu Bakar @ Zakaria, Md Zuki and Mohamed Mustapha, Noordin and Yusof, Norimah and Abdullah, Muhammad Nazrul Hakim (2004) The effect of topical application of Malaysian honey on burn wound healing. Jurnal Veterinar Malaysia, 16 (1&2). pp. 47-50. ISSN 9128-2506

Abstract / Synopsis

The efficacy of topical application of Malaysian honey on burn wound healing in Sprague-Dawley rats was investigated using 45 Sprague Dawley male rats weighing 200-300 g. Deep partial skin thickness burns were inflicted on the dorsal part of each animal. Two types of local honey (durian and Gelam) were applied twice a day in a quantity of 0.5 ml for each application, while control animals received no treatment. The rats were serially euthanisised at 3, 7, 14, 21 and 28 days post treatment for histological study. Histologically, early attenuation of inflammatory reaction and early reparative activities were observed in the honey treated wounds compared to control groups. Differential cells count showed a significant decreased in the number of inflammatory cells and increased vascularity in the honey treated wounds as early as 3 days post injury. In addition, epithelial regeneration appeared to be significant in gelam honey treated wound. This study showed that there was a significant acceleration of dermal repair in wound healing treated with durian and Gelam honey.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
Publisher: Veterinary Association Malaysia
Keywords: Bum wound; Honey; Rats
Depositing User: Azizan Arshad
Date Deposited: 03 Sep 2010 12:21
Last Modified: 18 Nov 2016 12:28
URI: http://psasir.upm.edu.my/id/eprint/7777
Statistic Details: View Download Statistic

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