A new cytotoxic carbazole alkaloid from Clausena excavata
Yap, Taufiq Yun Hin and Peh, Tian Hai and Ee, Gwendoline Cheng Lian and Rahmani, Mawardi and Md. Sukari, Mohd Aspollah and Ali, Abdul Manaf and Muse, Radzali (2007) A new cytotoxic carbazole alkaloid from Clausena excavata. Natural Product Research, 21 (9). pp. 810-813. ISSN 1478-6419; ESSN: 1478-6427
Official URL: http://dx.doi.org/10.1080/14786410701258875
A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1),together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line.
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