A new Cytotoxic Carbazole Alkaloid from Clausena excavata
Yap, Taufiq Yun Hin and Sukari, Mohd Aspollah and Ali, Abdul Manaf and Muse, Radzali and Rahmani, Mawardi and Ee, Gwendoline Cheng Lian and Peh, T. H. (2007) A new Cytotoxic Carbazole Alkaloid from Clausena excavata. Natural Product Research, 21 (9). pp. 810-813. ISSN 1478-6419
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Official URL: http://dx.doi.org/10.1080/14786410701258875
A new carbazole alkaloid, 3-carbomethoxy-2-hydroxy-7-methoxycarbazole, Clausine-TY (1),together with two known carbazole alkaloid, Clausine-H (2) and Clausine-B (3), were isolated from the ethyl acetate extract of the stem bark of the Malaysian Clausena excavata. The structures of these compounds were elucidated by spectroscopic analyses. The new carbazole alkaloid shows significant cytotoxicity against CEM-SS cell line.
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