Shamsudin, M. and Mohamed Alipiah, Norfarrah and Neela, Vasantha Kumari and Md Yusoff, Fatimah and Arshad, Aziz (2007) Analysis of essential gene changes in MRSA and non-MRSA strains inhibited by methanolic extract correlated to membrane permeabilising peptide. International Journal of Antimicrobial Agents, 29 (suppl.2). S634. ISSN 0924-8579
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Official URL: http://dx.doi.org/10.1016/S0924-8579(07)72030-7
Abstract
In this study, a methanolic extract derived from a marine organism was investigated for the effect on the growth of MRSA resistant to b-lactam antibiotics. The nucleotide sequence changes of essential genes inclusive of mecA, mecR1, 16sRNA, mprF and msR of the inhibited MRSA strains were determined. A potential antibacterial peptide with activity on permeabilising the membrane of MRSA strains was investigated through a cellular bioassay.
| Item Type: | Article |
|---|---|
| Faculty or Institute: | Faculty of Science |
| Publisher: | Elsevier |
| ID Code: | 7269 |
| Deposited By: | Najwani Amir Sariffudin |
| Deposited On: | 14 Jun 2010 17:18 |
| Last Modified: | 30 Jul 2010 12:27 |
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