Effect of intranasal attenuated Pasteurella multocida B:2 on haemorrhagic septicaemia in calves.

Khin, Myat Nwe and Saad, Mohd zamri and Mohamed Mustapha, Noordin and Abd Wahid, Mohd Effendy (2009) Effect of intranasal attenuated Pasteurella multocida B:2 on haemorrhagic septicaemia in calves. Online Journal of Veterinary Research, 13 (2). pp. 64-71. ISSN 1328-925X

Full text not available from this repository.

Abstract

This report describes the effect of vaccination with attenuated P. multocida B:2 on wild-type P. multocida B:2 infection in calves. Calves were given 5 ml intranasal 107 CFU/mL live attenuated gdhA derivative of P. multocida B:2. Untreated calves were then mingled with the vaccinated Group. Control untreated calves were kept separate. After 6 weeks, all calves were challenged intra-tracheally with 107 CFU/mL of live wild-type P. multocida B:2. At Post-Mortem none of the vaccinated or mingled calves had lesions whereas controls revealed pulmonary petechial haemorrhages with acute pneumonia patches with neutrophils. Both exposed and commingled calves showed significantly (p<0.05) higher levels of serum IgG. P. multocida B:2 were successfully isolated only from the control calves of Group 3. These findings suggest that intranasal exposures to live attenuated P. multocida B:2 prevented infection by wild-type P. multocida B:2 and may have protected susceptible calves.

Item Type:Article
Keyword:Intranasal; Attenuated Pasteurella multocida B:2; Infection.
Faculty or Institute:Faculty of Veterinary Medicine
Publisher:Online Journal of Veterinary Research
ID Code:7064
Deposited By: Azizan Arshad
Deposited On:04 Jun 2010 06:35
Last Modified:20 Nov 2013 04:28

Repository Staff Only: Edit item detail

Document Download Statistics

This item has been downloaded for since 04 Jun 2010 06:35.

View statistics for "Effect of intranasal attenuated Pasteurella multocida B:2 on haemorrhagic septicaemia in calves."


Universiti Putra Malaysia Institutional Repository

Universiti Putra Malaysia Institutional Repository is an on-line digital archive that serves as a central collection and storage of scientific information and research at the Universiti Putra Malaysia.

Currently, the collections deposited in the IR consists of Master and PhD theses, Master and PhD Project Report, Journal Articles, Journal Bulletins, Conference Papers, UPM News, Newspaper Cuttings, Patents and Inaugural Lectures.

As the policy of the university does not permit users to view thesis in full text, access is only given to the first 24 pages only.