Control of haemonchosis in Malaysian goats with closantel

Dorny, Pierre and Vercruysse, Jozef and Abu, Jalila and Abdullah Sani, Rehana and Symoens, Chantal (1994) Control of haemonchosis in Malaysian goats with closantel. Veterinary Parasitology, 53 (3-4). pp. 223-241. ISSN 0304-4017

Full text not available from this repository.

Official URL: http://dx.doi.org/10.1016/0304-4017(94)90186-4

Abstract

The therapeutic and prophylactic effects of closantel on natural infections with Haemonchus contortus were studied in goats in Peninsular Malaysia. Closantel was highly effective against H. contortus, either at a subcutaneous (s.c.) injection of 5.0 mg kg- ~ body weight (100%), or in an oral drench mixture with mebendazole at a dose of 10.0 mg kg-(99.2%), as indicated by faecal egg counts. H. contortus larvae were absent from faecal cultures for 5, 6 and 7 weeks following treatment with s.c. injections of closantel at doses of 2.5 mg kg- 1, 5.0 mg kg- ~ and 10.0 mg kg- 1 respectively, and for 6 weeks after treatment with closantel at 10.0 mg kg -1, given orally. Through its sustained activity, closantel not only prevented reinfection with H. contortus but also caused a dramatic reduction in pasture contamination. The potential utility of closantel in the strategic control of haemonchosis in goats, and as an alternative treatment for benzimidazoles and levamisole resistant H. contortus strains, is discussed.

Item Type:Article
Keyword:Haemonchus contortus, Goat, Control methods-Nematoda, Closantel, Sustained activity
Faculty or Institute:Faculty of Veterinary Medicine
Publisher:Elsevier Science
DOI Number:10.1016/0304-4017(94)90186-4
Altmetrics:http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/0304-4017(94)90186-4
ID Code:6245
Deposited By: Azizan Arshad
Deposited On:12 May 2010 04:50
Last Modified:19 Aug 2010 08:17

Repository Staff Only: Edit item detail

Document Download Statistics

This item has been downloaded for since 12 May 2010 04:50.

View statistics for "Control of haemonchosis in Malaysian goats with closantel"


Universiti Putra Malaysia Institutional Repository

Universiti Putra Malaysia Institutional Repository is an on-line digital archive that serves as a central collection and storage of scientific information and research at the Universiti Putra Malaysia.

Currently, the collections deposited in the IR consists of Master and PhD theses, Master and PhD Project Report, Journal Articles, Journal Bulletins, Conference Papers, UPM News, Newspaper Cuttings, Patents and Inaugural Lectures.

As the policy of the university does not permit users to view thesis in full text, access is only given to the first 24 pages only.