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Synthesis, characterization, and cytotoxicity of iron oxide nanoparticles


Citation

Kanagesan, Samikannu and Hashim, Mansor and Subramani, Tamilselvan and Mohammed Alitheen, Noorjahan Banu and Ismail, Ismayadi and Hajalilou, Abdollah and Kaiser, Ahsanul (2013) Synthesis, characterization, and cytotoxicity of iron oxide nanoparticles. Advances in Materials Science and Engineering, 2013. art. no. 710432. pp. 1-7. ISSN 1687-8434; ESSN: 1687-8442

Abstract

In order to study the response of human breast cancer cells' exposure to nanoparticle, iron oxide (α-Fe2O3) nanoparticles were synthesized by a simple low temperature combustion method using Fe(NO3)3·9H2O as raw material. X-ray diffraction studies confirmed that the resultant powders are pure α-Fe2O3. Transmission electron microscopy study revealed the spherical shape of the primary particles, and the size of the iron oxide nanoparticles is in the range of 19 nm. The magnetic hysteresis loops demonstrated that the sample exposed ferromagnetic behaviors with a relatively low coercivity. The cytotoxicity of α-Fe2O3 nanoparticle was also evaluated on human breast cancer cells to address the current deficient knowledge of cellular response to nanoparticle exposure.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Faculty of Engineering
Institute of Advanced Technology
Publisher: Hindawi Publishing Corporation
Depositing User: Nabilah Mustapa
Date Deposited: 05 Jun 2017 05:03
Last Modified: 05 Jun 2017 05:03
URI: http://psasir.upm.edu.my/id/eprint/52184
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