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Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less

Ab. Rahim, Noridayu and Hii, Yueh Feng and Abas, Faridah and Shaari, Khozirah and Lajis, Nordin (2011) Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less. International Food Research Journal, 18 (3). pp. 925-929. ISSN 1985-4668; ESSN: 2231-7546

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This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573.52 ± 6.2 mg GAE/100 g crude extract), in DPPH radical scavenging and Folin-Ciocalteu assays respectively, however, it failed to inhibit acetylcholinesterase in TLC bioautographic detection. The rest of plant extracts, included methanolic extract of stems, hexane extract of both leaves and stems, were detected to have acetylcholinesterase inhibitory properties. Hexane extract of both leaves and stems exhibited lower or negligible level of antioxidant activity and phenolic contents. Pluchea indica may provide a potential natural source of bioactive compounds, and maybe beneficial to the human health.

Item Type:Article
Keyword:Acetylcholinesterase; DPPH; Pluchea indica; Total phenolic content
Faculty or Institute:Faculty of Food Science and Biotechnology
Faculty of Science
Institute of Bioscience
Publisher:Faculty of Food Science and Technology, Universiti Putra Malaysia
ID Code:40678
Deposited By: Najah Mohd Ali
Deposited On:27 Nov 2015 10:52
Last Modified:27 Nov 2015 10:52

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