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In vitro antimicrobial activity of ethanol and water extracts of Cassia alata


Citation

Somchit, Muhammad Nazrul and Reezal, I. and Ismail, Elysha Nur and Mutalib, Abdul Rahim (2003) In vitro antimicrobial activity of ethanol and water extracts of Cassia alata. Journal of Ethnopharmacology, 84 (1). pp. 1-4. ISSN 0378-8741; ESSN: 1872-7573

Abstract

Crude ethanol and water extract of leaves and barks from Cassia alata were tested in vitro against fungi, (Aspergillus fumigatus and Microsporum canis), yeast (Candida albicans) and bacteria (Staphylococcus aereus and Escherichia coli). C. albicans showed concentration-dependent susceptibility towards both the ethanol and water extracts from the barks, but resistant towards the extracts of leaves. The degree of susceptibility varied, the water extract from barks showed bigger inhibition zone than the ethanol extracts (12–16 and 10–14 mm, diameter respectively). The growth of Aspergillus fumigatus and Microsporum canis were not affected by all types of the plant extracts. Results were comparable to standard antifungal drug Tioconazole (18 mm diameter) at equivalent concentration. The anti-bacterial activity of C. alata extracts on S. aureus was detected with only the leaves extracts using water and ethanol. The water extract exhibited higher antibacterial activity than the ethanol extract from leaves (inhibition zones of 11–14 and 9–11 mm, respectively). E. coli showed resistance to all types of extracts. Based on the current findings, it can be concluded that this plant has antimicrobial activity, which is as potent as standard antimicrobial drugs against certain microorganisms.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Faculty of Veterinary Medicine
DOI Number: https://doi.org/10.1016/S0378-8741(02)00146-0
Publisher: Elsevier
Keywords: Cassia alata; Antifungal; Antibacterial; In vitro
Depositing User: Nabilah Mustapa
Date Deposited: 17 Sep 2015 00:52
Last Modified: 23 Jul 2024 00:17
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/S0378-8741(02)00146-0
URI: http://psasir.upm.edu.my/id/eprint/40313
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