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The Chemical Constituents of Ficus benjamina Linn. and Their Biological Activities


Citation

Dafalla, Hassan Abdalla Almahy and Rahmani, Mawardi and Sukari, Mohd Aspollah and Ali, Abdul Manaf (2003) The Chemical Constituents of Ficus benjamina Linn. and Their Biological Activities. Pertanika Journal of Science & Technology, 11 (1). pp. 73-81. ISSN 0128-7680

Abstract / Synopsis

The leaves, bark and fruits of Ficus benjamina Linn. were subjected to extraction and isolation using chromatographic techniques to yield six compounds (cinnamic acid, lactose, naringenin, quercetin, caffeic acid and stigmasterol). The structures of the compounds were determined by spectroscopic techniques and by comparison with published data. The compounds were screened for antimicrobial activity against two species of bacteria (Bacillus cereus and Pseudomonas aeruginosa) and cytotoxic activity against T-lyrnphoblastic leukemic (CEM-SS) cell line. Caffeic acid exhibited strong cytotoxic activity with IC 50 value of 25 mg/mL.


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Additional Metadata

Item Type: Article
Publisher: Universiti Putra Malaysia Press
Keywords: Ficus berifamina, naringenin, quercetin, antimicrobial, cytotoxicity
Depositing User: Nur Izyan Mohd Zaki
Date Deposited: 02 Dec 2009 09:10
Last Modified: 27 May 2013 15:11
URI: http://psasir.upm.edu.my/id/eprint/3830
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