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The Chemical Constituents of Ficus benjamina Linn. and Their Biological Activities

Dafalla, Hassan Abdalla Almahy and Rahmani, Mawardi and Sukari, Mohd Aspollah and Ali, Abdul Manaf (2003) The Chemical Constituents of Ficus benjamina Linn. and Their Biological Activities. Pertanika Journal of Science & Technology, 11 (1). pp. 73-81. ISSN 0128-7680

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Abstract

The leaves, bark and fruits of Ficus benjamina Linn. were subjected to extraction and isolation using chromatographic techniques to yield six compounds (cinnamic acid, lactose, naringenin, quercetin, caffeic acid and stigmasterol). The structures of the compounds were determined by spectroscopic techniques and by comparison with published data. The compounds were screened for antimicrobial activity against two species of bacteria (Bacillus cereus and Pseudomonas aeruginosa) and cytotoxic activity against T-lyrnphoblastic leukemic (CEM-SS) cell line. Caffeic acid exhibited strong cytotoxic activity with IC 50 value of 25 mg/mL.

Item Type:Article
Keyword:Ficus berifamina, naringenin, quercetin, antimicrobial, cytotoxicity
Publisher:Universiti Putra Malaysia Press
ID Code:3830
Deposited By: Nur Izyan Mohd Zaki
Deposited On:02 Dec 2009 01:10
Last Modified:27 May 2013 07:11

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