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Preparation of astaxanthin nanodispersions using gelatin-based stabilizer systems

Anarjan, Navideh and Nehdi, Imededdine Arbi and Mohamed Sbihi, Hassen and Al-Resayes, Saud Ibrahim and Malmiri, Hoda Jafarizadeh and Tan, Chin Ping (2014) Preparation of astaxanthin nanodispersions using gelatin-based stabilizer systems. Molecules, 19 (9). pp. 14257-14265. ISSN 1420-3049

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Official URL: http://www.mdpi.com/1420-3049/19/9/14257

Abstract

The incorporation of lipophilic nutrients, such as astaxanthin (a fat soluble carotenoid) in nanodispersion systems can either increase the water solubility, stability and bioavailability or widen their applications in aqueous food and pharmaceutical formulations. In this research, gelatin and its combinations with sucrose oleate as a small molecular emulsifier, sodium caseinate (SC) as a protein and gum Arabic as a polysaccharide were used as stabilizer systems in the formation of astaxanthin nanodispersions via an emulsification-evaporation process. The results indicated that the addition of SC to gelatin in the stabilizer system could increase the chemical stability of astaxanthin nanodispersions significantly, while using a mixture of gelatin and sucrose oleate as a stabilizer led to production of nanodispersions with the smallest particle size (121.4 ± 8.6 nm). It was also shown that a combination of gelatin and gum Arabic could produce optimal astaxanthin nanodispersions in terms of physical stability (minimum polydispersity index (PDI) and maximum zeta-potential). This study demonstrated that the mixture of surface active compounds showed higher emulsifying and stabilizing functionality compared to using them individually in the preparation of astaxanthin nanodispersions.

Item Type:Article
Keyword:Astaxanthin nanodispersions; Emulsifying mixture; Emulsification-evaporation
Faculty or Institute:Faculty of Food Science and Technology
Publisher:MDPI
DOI Number:10.3390/molecules190914257
Altmetrics:http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules190914257
ID Code:35013
Deposited By: Nurul Ainie Mokhtar
Deposited On:28 Dec 2015 16:45
Last Modified:28 Dec 2015 16:45

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