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Polyphenols in Barringtonia racemosa and their protection against oxidation of LDL, serum and haemoglobin


Citation

Kong, Kin Weng and Mat Junit, Sarni and Ismail, Amin and Aminudin, Norhaniza and Abdul Aziz, Azlina (2014) Polyphenols in Barringtonia racemosa and their protection against oxidation of LDL, serum and haemoglobin. Food Chemistry, 146. pp. 85-93. ISSN 0308-8146; ESSN: 1873-7072

Abstract

The polyphenolic profiles and antioxidant activities of the water extracts of Barringtonia racemosa shoots (leaves and stems) were explored. Two methods, freeze drying and air drying, for preparation of the shoots, were also compared. Freeze drying was better as air drying caused 5–41% reduction of polyphenols. Three phenolic acids and three flavonoids were identified, using UHPLC. The descending order of polyphenols in the leaves and stems was gallic acid > ellagic acid > quercetin > protocatechuic acid > rutin > kaempferol. In vitro antioxidant analyses were performed using biological samples. In the LDL oxidation assay, B. racemosa leaf extract (IC50 = 73.0 μg/ml) was better than stem extract (IC50 = 226 μg/ml) at inhibiting the formation of TBARS and lipid hydroperoxides. Similar trends were observed for serum and haemoglobin oxidation. B. racemosa leaf extract was better than its stem extract in delaying the time required to oxidise haemoglobin to methaemoglobin. The high polyphenolic content of B. racemosa shoots could have contributed towards their antioxidative effects.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1016/j.foodchem.2013.09.012
Publisher: Elsevier Science Limited
Keywords: Natural products; Extraction; Barringtonia racemosa; Polyphenols; Lipid peroxidation; Haemoglobin oxidation; UHPLC
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 25 Dec 2015 04:20
Last Modified: 25 Dec 2015 04:20
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.foodchem.2013.09.012
URI: http://psasir.upm.edu.my/id/eprint/34957
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