Hypoxia inducible factor (HIF) activity reporter cell line
Norazizah Shafee. (2012) Hypoxia inducible factor (HIF) activity reporter cell line.
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The present invention relates to the construction of a new hypoxia inducible factor (HIF) responsive reporter gene construct, the genetic constructs and vectors containing the same. Further, the present invention relates to a stable cell line comprising the HIF responsive reporter construct, as well as methods and uses of the inventive constructs and cell lines to identify modulators of HIF activity.
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