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Phytochemical screening of Ayer Hitam Forest Reserve : Isolation of Ariskanin-A from Thottea corymbosa (Griff.) Ding Hou (Aristolochiaceae)


Citation

Yusoff, Nik Idris and Mat So'ad, Siti Zaiton and Suki, Ujang and Ibrahim, A. Zainuddin (2001) Phytochemical screening of Ayer Hitam Forest Reserve : Isolation of Ariskanin-A from Thottea corymbosa (Griff.) Ding Hou (Aristolochiaceae). Pertanika Journal of Tropical Agricultural Science, 24 (1). pp. 53-55. ISSN 1511-3701

Abstract / Synopsis

During a phytochemical screening of higher plants at Ayer Hitam Forest Reserve, Puchong, Selangor, we collected a large amount of sample of Thottea corymbosa roots for further investigation of its bioactive constituents. The plant is a shrub commonly used in herbal medicine and could easily be found along the open forest trails. The roots of the collected sample were consecutively extracted with petroleum-ether, chloroform and methanol followed by separation of the chloroform fraction by column chromatography and preparative thin-layer chromatography. In this study we reported the isolation of an aristolactam, Ariskanin-A with a toxicity value of LC50 <200 ppm in Brine-Shrimp Lethality Bioassay based on spectroscopic data and comparison with literature.


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Additional Metadata

Item Type: Article
Publisher: Universiti Putra Malaysia Press
Keywords: Thottea corymbosa; Aristolochiaceae; Ariskanin·A; aristolochic acid; Herbal medicine
Depositing User: Farhana Yusof
Date Deposited: 25 Nov 2009 12:23
Last Modified: 08 Sep 2015 11:40
URI: http://psasir.upm.edu.my/id/eprint/3313
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