Keyword Search:

A Simple and Clean Method for Methoxymethylation of Phenols

Ahmad, Faujan and Bruce, Malcolm J. (1989) A Simple and Clean Method for Methoxymethylation of Phenols. Pertanika, 12 (1). pp. 71-78.

[img] PDF
2524Kb

Abstract

A simple and clean procedure for the preparation of methoxymethyl ethers (MOM = CH2 OMe) of phenols having internally hydrogen bonded hydroxy groups is described. Thus treatment of 2,5-dihydroxybenzaldehyde (1) with a 1:1 mixture of methoxymethyl chloride-methyl acetate in ether at room temperature gives 2.5-bis( methoxymethoxy)benzaldehyde (2) in 57% yield; under similar conditions, the methoxymethyl ether (6) of salicylaldehyde was isolated in 75% yield. Yields of61-81 %, not optimised, of methoxymethyl ethers of several phenols lacking internal hydrogen bonding were also obtained.

Item Type:Article
Keyword:Methoxymethyl ethers of phenols
ID Code:2614
Deposited By: Nur Izzati Mohd Zaki
Deposited On:16 Nov 2009 06:42
Last Modified:27 May 2013 07:02

Repository Staff Only: Edit item detail

Document Download Statistics

This item has been downloaded for since 16 Nov 2009 06:42.

View statistics for "A Simple and Clean Method for Methoxymethylation of Phenols"

 
 
 
 

Universiti Putra Malaysia Institutional Repository is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.
Universiti Putra Malaysia Institutional Repository supports OAI 2.0 with a base URL of http://psasir.upm.edu.my/cgi/oai2
Best viewed using IE version 7.0 (and above) Mozilla Firefox version 3 (and above) with the resolution of 1024 x 768.