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Development of Bioaffinity Chromatography for Uricase Purification

Salleh, Abu Bakar (1980) Development of Bioaffinity Chromatography for Uricase Purification. Pertanika, 3 (2). pp. 97-102.

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Abstract

The uricase inhibitors urate, xanthine, oxonate and cyanurate were tried as ligands, for preparing bioaffinity support for chromatographic separation of uricase. Only derivatised purines showed inhibitory properties, whereas derivatised s-triazines seemed to lose their absorptive capacity. Chromatographic separation on a bioaffinity support produced higher yield and better purification of Uricase than conventional chromatographic technique.

Item Type:Article
Keyword:uricase, affinity chromatography
Faculty or Institute:Faculty of Environmental Studies
ID Code:2056
Deposited By: Nur Izyan Mohd Zaki
Deposited On:10 Nov 2009 00:19
Last Modified:27 May 2013 06:58

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