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Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae)

Abdullah, Rosmiati and Rahmani, Mawardi and Ali, Abdul Manaf and Ismail, H.B.M. and Sukari, Mohd Aspollah and Lian, Gwendoline Ee Cheng (2006) Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae). Malaysian Journal of Science, 25 (1). pp. 45-51. ISSN 1394-3065

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Abstract / Synopsis

Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone (1) and three sulphones - dambullin (2), sakambullin (3) and methylgerambullin (4), along with the common triterpene, stigmasterol. Compounds (1) (2) and (3) showed cytotoxic activity towards CEM-SS T-lymphoblastic cell lines. However, only dambullin (2) showed activity against pathogenic bacteria and fungi. We wish to report the isolation and bioassay results of the crude extracts and pure compounds.

Item Type: Article
Subject: Glycosmis
Subject: Plant bioactive compounds
Subject: Antioxidants
Divisions: Faculty of Science
Publisher: Faculty of Science, University of Malaya
Keywords: Antimicrobial; Antioxidant; Cytotoxic; Glycosmis chlorosperma; Rutaceae
Depositing User: Azwana Abdul Rahman
Date Deposited: 24 Oct 2011 23:27
Last Modified: 09 Dec 2015 10:34
URI: http://psasir.upm.edu.my/id/eprint/18299

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