Citation
Maulidiani, H.M and Shaari , Khozirah and Paetz , ChristiaN and Stanslas, Johnson and Abas, Faridah and Lajis, Nordin
(2009)
Naturally occurring labdane diterpene and benzofuran from Globba pendula.
Natural Product Communications, 4 (8).
pp. 1031-1036.
ISSN 1934-578X
Abstract
Phytochemical investigation on Globba pendula resulted in the isolation of a new naturally occurring 16-oxo-(8)17-12-labdadien-15,11-olide 1 and benzofuran-2-carboxaldehyde 2. Other known compounds including isoandrographolide, indirubin, vanillin, vanillic acid, 2(3H)-benzoxazolone, as well as beta-sitosteryl-beta-D-glucopyranoside, beta-sitosterol, and 7alpha-hydroxysitosterol were also isolated. The structures were established based on spectroscopic data and comparison with the literature. Furthermore, the compound isoandrographolide has demonstrated strong cytotoxic properties towards a panel of cancer cell lines (MCF-7, PC-3, and H-460) with the IC50 values of 7.9, 8.7, and 9.0 microM, respectively.
Download File
Full text not available from this repository.
|
Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Food Science and Technology |
| Publisher: | Natural Product Communications |
| Keywords: | Globba pendula; Zingiberaceae; Labdane diterpene. |
| Depositing User: | Khairil Ridzuan Khahirullah |
| Date Deposited: | 22 May 2013 03:21 |
| Last Modified: | 22 May 2013 03:21 |
| URI: | http://psasir.upm.edu.my/id/eprint/15783 |
| Statistic Details: | View Download Statistic |
Actions (login required)
 |
View Item |