Citation
Au, Lee Fong and Othman, Fauziah and Rahmat, Asmah and M., Rusnah and Besar, Idris and Vidyadaran, Sharmili and Md. Akim, Abdah and Goriman Khan, Mohd Azam Khan and Morteza , Saidi and Ahmad, Azfar Rizal
(2009)
Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm.
Malaysian Journal of Microscopy, 5 (1).
ISSN 1823-7010
Abstract
A biofilm is a multilayered complex microorganism, which attached on a surface and resistant to antibiotics. In this study, we examined the cytotoxicity of the HA biomaterial coated with gentamycin on S. aureus biofilm. The microtiter plate biofilm assay and catheter-associated biofilm had been described in this study. The surface morphology of S. aureus biofilm was examined under scanning electron microscope (SEM). The IC50 of gentamycincoated HA treated on S. aureus biofilm was 0.1mg/ml (100μg/ml).
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