Citation
Abd Hamid @ Abdul Razak, Roslida and Tay, C. E. and Ahmad, Zuraini and Chan, Pit Foong
(2010)
Anti-inflammatory and anti-nociceptive activities of the ethanolic extract of Annona muricata leaf.
Journal of Natural Remedies, 10 (2).
pp. 97-104.
ISSN 0972-5547; ESSN: 2320-3358
Abstract
Ethanolic extract of Annona muricata leaf (AML) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. AML exhibited significant and dose-dependent anti-inflammatory activity at a dose of 10, 30, 100 and 300 mg/kg when administered orally. It is also demonstrated that the intraperitoneal administration of AML at a dose of 30, 100 and 300 mg/kg produced significant inhibition of abdominal constriction induced with 0.6% (v/v) acetic acid in dose dependent manner. These results indicate that AML exhibits significant anti-inflammatory and antinociceptive effects.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science |
| Publisher: | Informatics Publishing Limited and Natural Remedies |
| Keywords: | Acetic acid induced writhing; Annona muricata; Carrageenan-induced oedema |
| Depositing User: | Raja Norazlinda Raja Azenam |
| Date Deposited: | 06 Dec 2014 05:07 |
| Last Modified: | 14 Aug 2017 09:13 |
| URI: | http://psasir.upm.edu.my/id/eprint/13148 |
| Statistic Details: | View Download Statistic |
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