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Comparison Of Chemical Profiles Of Black Cumin Seed (Nigella Sativa .L) Extracts And Evaluation Of Their Cytotoxic Effect On Breast Cancer Mcf-7 And Mda-Mb- 231 Cell Lines

Ghahramanloo, Kourosh Hasanzadeh (2009) Comparison Of Chemical Profiles Of Black Cumin Seed (Nigella Sativa .L) Extracts And Evaluation Of Their Cytotoxic Effect On Breast Cancer Mcf-7 And Mda-Mb- 231 Cell Lines. Masters thesis, Universiti Putra Malaysia.

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Abstract

Breast cancer is one of the main life-threatening diseases that a woman may have to face during her lifetime. This study was proposed in order to investigate the anticancer effects of the active ingredients of Nigella sativa crude extract, Thymoquinone (TQ), and Linoleic Acid (LA) on breast cancer MCF-7 and MDAMB- 231 cell lines. According to study design of this research, the study was performed in two parts respectively: 1. Extraction and Identification of Nigella sativa composition The main objective of this part of the present study was to compare the extract and oil composition of Iranian and Indian Nigella sativa L. extracted, using Super Critical Fluid Extraction (SFE) and solvent extraction.

Item Type:Thesis (Masters)
Subject:Black cumin - Therapeutic use
Subject:Breast - Cancer
Chairman Supervisor:Associate Professor Dr. Latiffah A. Latiff, M.D
Call Number:IB 2009 15
Faculty or Institute:Institute of Bioscience
ID Code:12058
Deposited By: Mohd Nezeri Mohamad
Deposited On:18 Jul 2011 15:10
Last Modified:27 May 2013 15:50

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