Potential of 3'-fluoro-3' deoxythymidine as a cellular proliferation marker in PET oncology examination
Hassan, Hishar and Price, Roger and Ahmad Saad, Fathinul Fikri and Lau, Eddie Wing Fai and Carpinelli, Assunta and Nordin, Abdul Jalil (2016) Potential of 3'-fluoro-3' deoxythymidine as a cellular proliferation marker in PET oncology examination. Pertanika Journal of Science & Technology, 24 (1). pp. 41-52. ISSN 0128-7680; ESSN: 2231-8526
Official URL: http://www.pertanika.upm.edu.my/Pertanika%20PAPERS...
Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker forenhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3'-fluoro-3'deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed.
Repository Staff Only: Edit item detail