Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities

Nafiah, Mohd Azlan (2001) Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities. Masters thesis, Universiti Pertanian Malaysia.

[img] PDF
1869Kb

Abstract

The phytochemical study on Glycosmis crassifolia (limau hutan) and G. chlorosperma (Rutaceae) involves extraction and separation by using various chromatographic methods, structural determination by spectroscopic techniques such as IR, NMR including 2D-NMR and MS. The structure of the compounds were elucidated by comparison with the previous works. Isolation work on roots of G. crassifolia yielded maculocidine (44). From the leaves, two more compounds were isolated and the structure elucidated. One of them was identified as a new alkaloid, glycofuranoxine (45) and the other one was stigmata-3,5,22-trien-3-01 (46). Further study on the twigs of the same plant afforded two known compounds including ergosta-4,6-dien-3-01 (47) and stigmata-5-en-3-01 (48). Detail study on the leaves extract of Glycosmis chlorosperma yielded two compounds. One of them was identified as a new compound, 5-hydroxy-7,4'dimethoxy- 8-(-3"-methylbut-2"-enyl)f1avanone (49) and the other one was known as dambullin (50). Crude extract from various plant were screened for antifungal activity using poison food method against Sclerotium rolfsii. However, the petroleumether, chloroform and methanol extract of the roots, leaves and twigs of the plant failed to show any activity in inhibition of mycelial growth and sclerotial germination.

Item Type:Thesis (Masters)
Subject:Glycosmis
Subject:Chemical elements - Spectra
Chairman Supervisor:Professor Dr. Mawardi bin Rahmani, PhD
Call Number:FSAS 2001 30
Faculty or Institute:Faculty of Science and Environmental Studies
ID Code:9284
Deposited By: Tuan Norasiah Tuan Yaacob
Deposited On:19 Jan 2011 04:31
Last Modified:30 Sep 2013 00:38

Repository Staff Only: Edit item detail

Document Download Statistics

This item has been downloaded for since 19 Jan 2011 04:31.

View statistics for "Chemical Constituents of Glycosmis Crassifolia and G. Chlorosperma (Rutaceae) and Their Biological Activities"


Universiti Putra Malaysia Institutional Repository

Universiti Putra Malaysia Institutional Repository is an on-line digital archive that serves as a central collection and storage of scientific information and research at the Universiti Putra Malaysia.

Currently, the collections deposited in the IR consists of Master and PhD theses, Master and PhD Project Report, Journal Articles, Journal Bulletins, Conference Papers, UPM News, Newspaper Cuttings, Patents and Inaugural Lectures.

As the policy of the university does not permit users to view thesis in full text, access is only given to the first 24 pages only.