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Adverse effects of imidocarb dipropionate (Imizol) in a dog

Abdullah, A. Salam and Abdul Rahman, Sheikh Omar and Desmond, Baggot J. and Saad, Mohd Zamri (1984) Adverse effects of imidocarb dipropionate (Imizol) in a dog. Veterinary Research Communications, 8 (1). pp. 55-59. ISSN 0165-7380; ESSN: 1573-7446

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One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action.

Item Type:Article
Keyword:Imidocarb; Imidocarb dipropionate
Faculty or Institute:Faculty of Veterinary Medicine
Publisher:Kluwer Academic Publishers
DOI Number:10.1007/BF02214695
ID Code:5593
Deposited By: Azizan Arshad
Deposited On:14 Apr 2010 14:54
Last Modified:23 Sep 2015 09:46

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