UPM Institutional Repository

Major components of fish immunity: a review


Citation

Nawi, Mohd Firdaus and Saad, Mohd Zamri (2016) Major components of fish immunity: a review. Pertanika Journal of Tropical Agricultural Science, 39 (4). pp. 393-420. ISSN 1511-3701; ESSN: 2231-8542

Abstract

Fish are fascinating creatures with a certain degree of immunity comparable to those of mammals. The fish's immune system consists of two major components, innate and adaptive immunities. Innate immunity is non-specific and acts as the primary line of protection against pathogen invasion while adaptive immunity is more specific to a certain pathogen/following adaptation. Innate immunity consists of the non-specific cellular and the non-specific humoral components. The non-specific cellular component consists of toll-like receptors (TLRs), macrophages, neutrophils, eosinophils and non-specific cytotoxic cell while the non-specific humoral component involves lysozyme, the complement, interferons, C-reactive proteins, transferrins and lectins. They work together at the initial stage to prevent pathogen invasion. On the other hand, the adaptive immune system consists of highly specilised systemic cells and processes that are separated into two main components: the humoral and cellular components. Three types of antibodies, the IgM, IgD and IgT, are the major constituents of the humoral immunity, which act on invaded extracellular pathogens. The cytotoxic T-lymphocyte cells are the major component of the cellular immunity that frequently kills virus-infected and intracellular bacterial or parasitic-infected cells. Both innate and adaptive immunities complement each other in the host's attempt to prevent infection.


Download File

[img]
Preview
PDF
01 JTAS 0710-2015 - Review Article.pdf

Download (2MB) | Preview

Additional Metadata

Item Type: Article
Divisions: Faculty of Veterinary Medicine
Publisher: Universiti Putra Malaysia Press
Keywords: Immunity; Component; Mechanism; Fish
Depositing User: Nabilah Mustapa
Date Deposited: 30 Dec 2016 03:54
Last Modified: 30 Dec 2016 03:54
URI: http://psasir.upm.edu.my/id/eprint/49690
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item