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Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders

Daud Ahmad Israf Ali. (2012) Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders.

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Abstract

The present invention relates to an analog of curcumin, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) or a pharmaceutically acceptable salt, solvate or derivative thereof, for use in treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction. Furthermore provided are methods of treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction using BHMC or a pharmaceutically acceptable salt, solvate or derivative thereof. The invention provides also a method for attenuating endothelial dysfunction in an endothelial cell and/or attenuating the hallmarks of endothelial dysfunction in an endothelial cell.

Item Type:Patent
Keyword:Curcumin analog; BHMC; Pharmaceutically acceptable salt; Endothelial dysfunction
Faculty or Institute:Faculty of Veterinary Medicine
Application Number:PI2012003491
Filing Date:2012-08-02
ID Code:33360
Deposited By: Nurul Ainie Mokhtar
Deposited On:05 Feb 2015 12:21
Last Modified:05 Feb 2015 12:21

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