Keyword Search:


Bookmark and Share

GLP-1 promoter mediated insulin expression for the treatment of diabetes.

Zalinah Ahmad. (2010) GLP-1 promoter mediated insulin expression for the treatment of diabetes.

Full text not available from this repository.

Abstract

Insulin gene therapy is one of many envisioned alternative treatments of diabetes. Diabetes gene therapy would be possible if insulin could be produced in a regulated and specifically in a sensitive manner dependent on the blood glucose level.Therefore, the present invention relates to a method for the isolation of GLP-1 expressing cells, to nucleic acids sequence construction or vectors useful for isolating GLP-1 expressing cell and to the GLP-1 expressing cells isolated therewith. Furthermore, the inventions relates to a method of nucleic acids sequence construction or vectors under the control of the GLP-1 promoter expressing insulin in a recombinant GLP-1 expressing cell line. The cells of the present invention are particular useful for the treatment of diabetes and may be used in a gene therapy approach to treat diabetes and other disorders related to the nutrient metabloism.

Item Type:Patent
Keyword:GLP-1; Insulin; Diabetes.
Faculty or Institute:Faculty of Medicine and Health Science
ID Code:32198
Deposited By: Junaini Mohd Yusof
Deposited On:07 Oct 2014 09:48
Last Modified:07 Oct 2014 09:48

Repository Staff Only: Edit item detail

Document Download Statistics

This item has been downloaded for since 07 Oct 2014 09:48.

View statistics for "GLP-1 promoter mediated insulin expression for the treatment of diabetes. "