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18[F]FDG-PET/CT is a useful molecular marker in evaluating tumour aggressiveness: a revised understanding of an in-vivo FDG-PET imaging that alludes the alteration of cancer biology

Ahmad Saad, Fathinul Fikri and Nordin, Abdul Jalil and Lau, W. F. E. (2013) 18[F]FDG-PET/CT is a useful molecular marker in evaluating tumour aggressiveness: a revised understanding of an in-vivo FDG-PET imaging that alludes the alteration of cancer biology. Cell Biochemistry and Biophysics, 66 (1). pp. 37-43. ISSN 1085-9195; ESSN: 1559-0283

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Abstract

Molecular imaging employing 18 [F] FDG-PET/CT enables in-vivo visualization, characterisation and measurement of biological process in tumour at the molecular and cellular level. In oncology, this approach can be directly applied as translational biomarkers of disease progression. In this article, the improved roles of FDG as an in-vivo glycolytic marker which reflect biological changes across in-vitro cellular environment are discussed.

Item Type:Article
Keyword:In vivo; 18[F]FDG-PET/CT; Tumour aggressiveness; Molecular marker; Tumour biology
Faculty or Institute:Centre For Diagnostic Nuclear Imaging
Publisher:Springer
DOI Number:10.1007/s12013-012-9395-5
Altmetrics:http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1007/s12013-012-9395-5
ID Code:30896
Deposited By: Umikalthom Abdullah
Deposited On:13 Aug 2015 15:59
Last Modified:08 Sep 2015 10:13

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