Sudden death in a case of sickle cell anemia: post-mortem computed tomography and autopsy correlation from a radiologist's perspective
Abdul Rashid, Saiful Nizam and Krauskopf, Astrid and Vonlanthen, Bruno and Thali, Michael J. and Ruder, Thomas D. (2013) Sudden death in a case of sickle cell anemia: post-mortem computed tomography and autopsy correlation from a radiologist's perspective. Legal Medicine, 15 (4). 213-216. ISSN 1344-6223; ESSN: 1873-4162
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Official URL: http://www.legalmedicinejournal.com/article/S1344-...
Sickle cell anemia (SCA) is a hemolytic disease characterized by the production of abnormal hemoglobin chains and distorted red blood cell morphology or sickling. "Sickle cell crisis" includes vaso-occlusive crisis, a plastic crisis, sequestration crisis, haemolytic crisis and often culminating in serious complications, organ damage and even sudden death. Post-mortem computed tomography (PMCT) findings of sickle cell disease have never been reported in literature. This case of sudden death from acute hemolytic crisis in SCA where post-mortem computed tomography (PMCT) and autopsy findings complemented each other, both revealing findings invisible to the other and both crucial to the case.
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